A B O U T

INVENTIONIS

인벤셔니스는 신약 개발 연구 대행 및 원료의약품의 합성 서비스 제공 하고 있습니다.

사업 분야 

신규화합물 합성 인력 제휴 (FTE: Full Time Equivalent)
GMP, Non-GMP 원료의약품 생산대행
CHEMICAL SOLUTION 
BIOLOGY SOLUTION (ADME, DMPK, 약효평가, PK-PD, 독성평가)
Formulation & 분석법개발 







DISCOVERY CHEMISTRY

Medicinal Chemistry
Synthetic Chemistry
Library Chemistry
Peptide Chemistry
Analytic Chemistry
Carbohydrates Chemistry

DISCOVERY BIOLOGY

In-vitro Biology
ADME /PK
Microbiology
In-vitro Pharmacology
Pre-clinical Safety Evaluation

CHEMICAL DEVELOPMENT

Route Scouting
Polymorph Screening
Process Design and Development (CMC)
Process Optimization
Scale-up Studies
cGMP Contract Manufacturing
RSM, KSM, API, contract manufacturing

FORMULATION

Pre-Formulation
Formulation Development
cGMP Manufacturing


‌서비스 관련 질의 응답 : info@inventionis,com


In-Vitro Biology

Oncology Models

 Xenograft : Breast, Ovarian, Colon  
Syngenic : Melanoma, Multiple Myeloma, Lung etc.

Fibrosis Models

NASH (Non-Alcoholic Steatohepatitis)
AMLN diet-induced NASH Model*  주요 서비스
CCl4 induced Liver Fibrosis
UUO , (unilateral Ureteral obstruction)


Pain Models

Neuropathic (CCI, Chung , STZ and paclitaxel)
Brennan model
Inflammatory (CFA, Carrageenan induced mechanical allodynia or thermal hyperalgesia) 

‌Inflammation Models

Psoriasis (Imiquimod, IL-23 induced)
Delayed type hypersensitivity(Oxazolone)
MOG ( Myelin Oligodendrocyte Glycoprotein )
‌Induced EAE (Experimental Autoimmune Encephalomyelitis)
DDS (Dextran Sulphate Sodium) induced colitis
Inflammatory cytokines from plasma and tissues

‌CVS and Metavolic diseases models

DIO ( Diet Induced Obesity ) in mice
Dyslipidemia model
OGTT, ipGTT, ivGTT in mice and rats
‌Ghrelinemia model
CKD ( Chronic Kidney Disease )
Monocrotaline-induced PAH (Pulmonary Arterial Hypertension)

‌PK-PD & Toxicity Studies

Oral, IV, IP, SC administration
MTD and repeat dose toxicity studies in rodents ( Non-GLP)
PK& MTD studies in tumor bearing mice

Key intermediates (For generic & new drugs)

Key intermediate , Ligan & Catalyst  구매

‌주문가능 리스트

‌Ligand & Catalyst


APIs, Intermediates 



Contact

You can contact me via the form, or just send me an e-mail directly at
info@inventionis.com

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